[SELF] Worked out that someone with Down's Syndrome weighs 2 grams more on average due to extra chromosomes

I'll wait to see this on r/goingtohellforthis...

/r/jesuschristreddit

Makes sense because most of the HAES crowd is retarded.

I remember the fat logic around this. One of the very few occasions fat logic really made me angry. I work with people with DS and weight is a massive issue for most. The biggest problem is that they struggle understand the nuances of language "you're looking great" after a modicum of weigh loss often translates "I don't need to work so hard now" and the head fuck when bitching about "making them conform to societal standards" when we are literally trying to stop their health decline to the point where illness and death is a likely outcome.

Fuck people who think they know what's best for someone else without understanding the context. And double fuck those who publicly denounce people wanting to make positive change, especially those with disabilities.

So is Fat Logic a "bad" sub? I couldn't tell.

This needs to be upvoted more. The calculation may be right in accounting for the extra weight from all the chromosomes; however it fails to account for the fact that people with Down syndrome will have very different morphology and these will most likely contribute to a lot MORE difference than just the two grams from the chromosome alone.

The calculation was almost analogous to saying that men would weigh 1-2 grams less than women on average because their Y chromosomes are lighter than X chromosome.

I doubt that they cause an increase in cell volume since there's plenty of space filled by nothing but cytoplasm

Cells don't have a set constant volume. Water will freely diffuse in and out of a cell to keep osmotic pressure balanced across the membrane, and osmotic pressure is determined by how much solute is inside the cell. The effect of adding an extra chromosome into the cell will depend on how a chromosome interact with water molecules, whether it attract or repel them.

Fair point, but there are probably an almost equal number of muscle and liver cells that are polyploid (have more than 2 pairs of each chromosome) to cancel it out or at least make that difference less significant.

Isn't 30 trillion 3x10¹³ ? 3x10¹⁰ is only 30 billion.